Investigation of the oxidative stress condition for occupational exposure to methyl methacrylate.
Identifieur interne : 000114 ( Main/Exploration ); précédent : 000113; suivant : 000115Investigation of the oxidative stress condition for occupational exposure to methyl methacrylate.
Auteurs : Bu Ra Soykut [Turquie] ; Onur Erdem [Turquie] ; Cemal Akay [Turquie] ; Bülent Pi Kin [Turquie]Source :
- Toxicology and industrial health [ 1477-0393 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Catalase (sang), Dentistes (MeSH), Espèces réactives de l'oxygène (métabolisme), Exposition professionnelle (effets indésirables), Femelle (MeSH), Glutathione peroxidase (sang), Humains (MeSH), Malonaldéhyde (sang), Mâle (MeSH), Méthacrylate de méthyle (toxicité), Stress oxydatif (effets des médicaments et des substances chimiques), Superoxide dismutase (sang), Études cas-témoins (MeSH).
- MESH :
- effets des médicaments et des substances chimiques : Stress oxydatif.
- effets indésirables : Exposition professionnelle.
- métabolisme : Espèces réactives de l'oxygène.
- sang : Catalase, Glutathione peroxidase, Malonaldéhyde, Superoxide dismutase.
- toxicité : Méthacrylate de méthyle.
- Adulte, Adulte d'âge moyen, Dentistes, Femelle, Humains, Mâle, Études cas-témoins.
English descriptors
- KwdEn :
- Adult (MeSH), Case-Control Studies (MeSH), Catalase (blood), Dentists (MeSH), Female (MeSH), Glutathione Peroxidase (blood), Humans (MeSH), Male (MeSH), Malondialdehyde (blood), Methylmethacrylate (toxicity), Middle Aged (MeSH), Occupational Exposure (adverse effects), Oxidative Stress (drug effects), Reactive Oxygen Species (metabolism), Superoxide Dismutase (blood).
- MESH :
- chemical , blood : Catalase, Glutathione Peroxidase, Malondialdehyde, Superoxide Dismutase.
- chemical , metabolism : Reactive Oxygen Species.
- chemical , toxicity : Methylmethacrylate.
- adverse effects : Occupational Exposure.
- drug effects : Oxidative Stress.
- Adult, Case-Control Studies, Dentists, Female, Humans, Male, Middle Aged.
Abstract
The purpose of this study is the evaluation of possible toxicological effects on dental personnel, who are exposed to the production materials of prostheses during their entire working life. In this study, the level of methyl methacrylate (MMA) in ambient air was measured as an indicator of external exposure on the personnel. In order to evaluate the possible toxic effects of oxidative stress, which is thought to play an important role in the formation process of many diseases such as cancer, blood samples of volunteers were examined via the ultraviolet-spectroscopic determination of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase antioxidant enzyme activities, comparing occupationally MMA-exposed ( n = 69) and control ( n = 67) groups. In these groups, malondialdehyde (MDA) and glutathione levels were also determined by the same method. The results showed that SOD activity and MDA and glutathione levels were significantly higher in the exposed group when compared with the control group ( p < 0.001). A significant decrease was determined in the glutathione peroxidase activities of the exposed group ( p < 0.05). No significant difference in CAT activities between the groups has been found. When the results obtained in the study are considered, it is suggested that an adaptive response might be developed by dental technicians against low-level MMA exposure.
DOI: 10.1177/0748233716659840
PubMed: 27449027
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Investigation of the oxidative stress condition for occupational exposure to methyl methacrylate.</title><author><name sortKey="Soykut, Bu Ra" sort="Soykut, Bu Ra" uniqKey="Soykut B" first="Bu Ra" last="Soykut">Bu Ra Soykut</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Erdem, Onur" sort="Erdem, Onur" uniqKey="Erdem O" first="Onur" last="Erdem">Onur Erdem</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Akay, Cemal" sort="Akay, Cemal" uniqKey="Akay C" first="Cemal" last="Akay">Cemal Akay</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Pi Kin, Bulent" sort="Pi Kin, Bulent" uniqKey="Pi Kin B" first="Bülent" last="Pi Kin">Bülent Pi Kin</name><affiliation wicri:level="1"><nlm:affiliation>2 Department of Prosthodontics, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>2 Department of Prosthodontics, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:27449027</idno><idno type="pmid">27449027</idno><idno type="doi">10.1177/0748233716659840</idno><idno type="wicri:Area/Main/Corpus">000139</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000139</idno><idno type="wicri:Area/Main/Curation">000139</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000139</idno><idno type="wicri:Area/Main/Exploration">000139</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Investigation of the oxidative stress condition for occupational exposure to methyl methacrylate.</title><author><name sortKey="Soykut, Bu Ra" sort="Soykut, Bu Ra" uniqKey="Soykut B" first="Bu Ra" last="Soykut">Bu Ra Soykut</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Erdem, Onur" sort="Erdem, Onur" uniqKey="Erdem O" first="Onur" last="Erdem">Onur Erdem</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Akay, Cemal" sort="Akay, Cemal" uniqKey="Akay C" first="Cemal" last="Akay">Cemal Akay</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Pi Kin, Bulent" sort="Pi Kin, Bulent" uniqKey="Pi Kin B" first="Bülent" last="Pi Kin">Bülent Pi Kin</name><affiliation wicri:level="1"><nlm:affiliation>2 Department of Prosthodontics, Gulhane Military Academy of Medicine, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>2 Department of Prosthodontics, Gulhane Military Academy of Medicine, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author></analytic><series><title level="j">Toxicology and industrial health</title><idno type="eISSN">1477-0393</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Case-Control Studies (MeSH)</term><term>Catalase (blood)</term><term>Dentists (MeSH)</term><term>Female (MeSH)</term><term>Glutathione Peroxidase (blood)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Malondialdehyde (blood)</term><term>Methylmethacrylate (toxicity)</term><term>Middle Aged (MeSH)</term><term>Occupational Exposure (adverse effects)</term><term>Oxidative Stress (drug effects)</term><term>Reactive Oxygen Species (metabolism)</term><term>Superoxide Dismutase (blood)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Catalase (sang)</term><term>Dentistes (MeSH)</term><term>Espèces réactives de l'oxygène (métabolisme)</term><term>Exposition professionnelle (effets indésirables)</term><term>Femelle (MeSH)</term><term>Glutathione peroxidase (sang)</term><term>Humains (MeSH)</term><term>Malonaldéhyde (sang)</term><term>Mâle (MeSH)</term><term>Méthacrylate de méthyle (toxicité)</term><term>Stress oxydatif (effets des médicaments et des substances chimiques)</term><term>Superoxide dismutase (sang)</term><term>Études cas-témoins (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Catalase</term><term>Glutathione Peroxidase</term><term>Malondialdehyde</term><term>Superoxide Dismutase</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Reactive Oxygen Species</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Methylmethacrylate</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Occupational Exposure</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Oxidative Stress</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Stress oxydatif</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Exposition professionnelle</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Espèces réactives de l'oxygène</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Catalase</term><term>Glutathione peroxidase</term><term>Malonaldéhyde</term><term>Superoxide dismutase</term></keywords><keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Méthacrylate de méthyle</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Case-Control Studies</term><term>Dentists</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Dentistes</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Études cas-témoins</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this study is the evaluation of possible toxicological effects on dental personnel, who are exposed to the production materials of prostheses during their entire working life. In this study, the level of methyl methacrylate (MMA) in ambient air was measured as an indicator of external exposure on the personnel. In order to evaluate the possible toxic effects of oxidative stress, which is thought to play an important role in the formation process of many diseases such as cancer, blood samples of volunteers were examined via the ultraviolet-spectroscopic determination of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase antioxidant enzyme activities, comparing occupationally MMA-exposed ( n = 69) and control ( n = 67) groups. In these groups, malondialdehyde (MDA) and glutathione levels were also determined by the same method. The results showed that SOD activity and MDA and glutathione levels were significantly higher in the exposed group when compared with the control group ( p < 0.001). A significant decrease was determined in the glutathione peroxidase activities of the exposed group ( p < 0.05). No significant difference in CAT activities between the groups has been found. When the results obtained in the study are considered, it is suggested that an adaptive response might be developed by dental technicians against low-level MMA exposure.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27449027</PMID><DateCompleted><Year>2017</Year><Month>08</Month><Day>03</Day></DateCompleted><DateRevised><Year>2017</Year><Month>08</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1477-0393</ISSN><JournalIssue CitedMedium="Internet"><Volume>33</Volume><Issue>1</Issue><PubDate><Year>2017</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Toxicology and industrial health</Title><ISOAbbreviation>Toxicol Ind Health</ISOAbbreviation></Journal><ArticleTitle>Investigation of the oxidative stress condition for occupational exposure to methyl methacrylate.</ArticleTitle><Pagination><MedlinePgn>61-66</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1177/0748233716659840</ELocationID><Abstract><AbstractText>The purpose of this study is the evaluation of possible toxicological effects on dental personnel, who are exposed to the production materials of prostheses during their entire working life. In this study, the level of methyl methacrylate (MMA) in ambient air was measured as an indicator of external exposure on the personnel. In order to evaluate the possible toxic effects of oxidative stress, which is thought to play an important role in the formation process of many diseases such as cancer, blood samples of volunteers were examined via the ultraviolet-spectroscopic determination of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase antioxidant enzyme activities, comparing occupationally MMA-exposed ( n = 69) and control ( n = 67) groups. In these groups, malondialdehyde (MDA) and glutathione levels were also determined by the same method. The results showed that SOD activity and MDA and glutathione levels were significantly higher in the exposed group when compared with the control group ( p < 0.001). A significant decrease was determined in the glutathione peroxidase activities of the exposed group ( p < 0.05). No significant difference in CAT activities between the groups has been found. When the results obtained in the study are considered, it is suggested that an adaptive response might be developed by dental technicians against low-level MMA exposure.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Soykut</LastName><ForeName>Buğra</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Erdem</LastName><ForeName>Onur</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Akay</LastName><ForeName>Cemal</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>1 Department of Pharmaceutical Toxicology, Gulhane Military Academy of Medicine, Ankara, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pişkin</LastName><ForeName>Bülent</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>2 Department of Prosthodontics, Gulhane Military Academy of Medicine, Ankara, Turkey.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>07</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Toxicol Ind Health</MedlineTA><NlmUniqueID>8602702</NlmUniqueID><ISSNLinking>0748-2337</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017382">Reactive Oxygen Species</NameOfSubstance></Chemical><Chemical><RegistryNumber>196OC77688</RegistryNumber><NameOfSubstance UI="D020366">Methylmethacrylate</NameOfSubstance></Chemical><Chemical><RegistryNumber>4Y8F71G49Q</RegistryNumber><NameOfSubstance UI="D008315">Malondialdehyde</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.11.1.6</RegistryNumber><NameOfSubstance UI="D002374">Catalase</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.11.1.9</RegistryNumber><NameOfSubstance UI="D005979">Glutathione Peroxidase</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.15.1.1</RegistryNumber><NameOfSubstance UI="D013482">Superoxide Dismutase</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002374" MajorTopicYN="N">Catalase</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003815" MajorTopicYN="N">Dentists</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005979" MajorTopicYN="N">Glutathione Peroxidase</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008315" MajorTopicYN="N">Malondialdehyde</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020366" MajorTopicYN="N">Methylmethacrylate</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016273" MajorTopicYN="N">Occupational Exposure</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018384" MajorTopicYN="N">Oxidative Stress</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017382" MajorTopicYN="N">Reactive Oxygen Species</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013482" MajorTopicYN="N">Superoxide Dismutase</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antioxidant</Keyword><Keyword MajorTopicYN="N">adaptive response</Keyword><Keyword MajorTopicYN="N">genotoxicity</Keyword><Keyword MajorTopicYN="N">glutathione</Keyword><Keyword MajorTopicYN="N">oxidative stress</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>7</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>7</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27449027</ArticleId><ArticleId IdType="pii">0748233716659840</ArticleId><ArticleId IdType="doi">10.1177/0748233716659840</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Turquie</li></country></list><tree><country name="Turquie"><noRegion><name sortKey="Soykut, Bu Ra" sort="Soykut, Bu Ra" uniqKey="Soykut B" first="Bu Ra" last="Soykut">Bu Ra Soykut</name></noRegion><name sortKey="Akay, Cemal" sort="Akay, Cemal" uniqKey="Akay C" first="Cemal" last="Akay">Cemal Akay</name><name sortKey="Erdem, Onur" sort="Erdem, Onur" uniqKey="Erdem O" first="Onur" last="Erdem">Onur Erdem</name><name sortKey="Pi Kin, Bulent" sort="Pi Kin, Bulent" uniqKey="Pi Kin B" first="Bülent" last="Pi Kin">Bülent Pi Kin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SuicidDentistV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000114 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000114 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SuicidDentistV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:27449027
|texte= Investigation of the oxidative stress condition for occupational exposure to methyl methacrylate.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27449027" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SuicidDentistV1
| This area was generated with Dilib version V0.6.39. |  |